Early breast cancer.

Early Detection of Breast Cancer among Women in Mazandaran, Iran

Background and purpose: After lung cancer, breast cancer, among the prevalent cancers of the world is of the most widespread disease among women. It is the most common cause of mortality among women. This study aimed to analyze the results using breast cancer screening methods among women over 20 years old. Materials and methods: The present study is a cross-sectional-descriptive research. The ...

BIRC5 Genomic Copy Number Variation in Early-Onset Breast Cancer

Background: Baculoviral inhibitor of apoptosis repeat-containing 5 (BIRC5) gene is an inhibitor of apoptosis that expresses in human embryonic tissues but it is absent in most healthy adult tissues. The copy number of BIRC5 has been indicated to be highly increased in tumor tissues; however, its association with the age of onset in breast cancer is not well understood. Methods: Forty tumor tiss...

Partial breast irradiation for early breast cancer.

BACKGROUND Breast conserving therapy for women with breast cancer consists of local excision of the tumour (achieving clear margins) followed by radiation therapy (RT). RT is given to sterilize tumour cells that may remain after surgery to decrease the risk of local tumour recurrence. Most true recurrences occur in the same quadrant as the original tumour. Whole breast RT may not protect agains...

Early Diagnosis of Breast Cancer

Vaccines and early breast cancer

Our recent work has cast an exciting new light on the expression of cancer/testis (CT) genes in breast cancer and its precursor lesions. Cancer/testis (CT) genes, normally expressed only in the human germ line but activated in various malignancies, are immunogenic in cancer patients. Their tumor-restricted expression pattern makes these proteins promising clinical reagents for anticancer immuno...